Q-Line

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On-demand sequencing for applied purposes

Launching with the GridION Q, the ISO9001-qualified Q-Line sequencing portfolio from Oxford Nanopore delivers all of the benefits of real-time, on-demand nanopore sequencing in a locked-down, standardised format — enabling the implementation of routine, long-term workflows for in-house validated assays.

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Proven, locked-down technology

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Compliance with 21 CFR Part 11 and EU GMP Annex 11

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Full operating software and consumable version support and supply for at least 3 years post release

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Clearly defined, visible product update pathway and implementation support

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ISO 9001:2015 certified product manufacturing process

Is Q-Line right for me?

Locked-down Q-Line products are suitable for all long-term, internally validated sequencing workflows where rapid and reliable results are required, including:

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Pharmaceutical research

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Clinical research

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Veterinary diagnostics

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Environmental monitoring

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Outbreak surveillance

Sequencing devices

GridION Q Front Black

GridION Q

A locked-down version of the flexible, high-throughput benchtop sequencing system with integrated compute.

With the capacity to run five independent MinION Flow Cells on demand, the GridION Q offers the same flexibility and specification as the established GridION Mk1 platform, but with fixed software and chemistry updates — allowing users to setup robust, long-term, in-house validated sequencing workflows. Integrated high-performance GPUs alleviate data analysis bottlenecks.

Library preparation

Q-Line Ligation Kit

Q-Line Ligation Sequencing Kit

A versatile library preparation kit combining high sequencing yield and control over read length with streamlined, automatable processing.

Q-Line Native Barcoding kit

Q-Line Native Barcoding Expansion

Enabling up to 24 samples to be run on a single flow cell, this kit allows maximum data generation and lowers the cost per sample. As PCR is not required, samples can be multiplexed without loss of base modification information.

Q-Line Rapid barcoding kit

Q-Line Rapid Barcoding Kit

A simple and rapid library preparation method, with barcoding for up to 96 genomic DNA samples.

Q-Line wash kit

Q-Line Flow Cell Wash Kit

This kit enables you to wash and reuse flow cells for multiple successive runs, maximising your sequence data across the life of the flow cell.

Cas9 Kit

Q-Line Cas9 Sequencing Kit

This kit offers comprehensive targeted sequencing of genomic regions using CRISPR-Cas9 — empowering you in regulated environments to verify both on- and off-target editing events in cell lines. As an alternative to targeted locus amplification (TLA), which has difficulty with off-target detection and structural variant identification, this kit offers long read lengths spanning insertion sites and does not require primers or amplification.

Receive comprehensive, enhanced support when you need it, for confident integration of nanopore sequencing into routine, long-term workflows. IQ/OQ/PQ options, either through detailed self-guide instructions or with the support of an experienced Oxford Nanopore specialist, ensure your devices and reagents perform to the high standard you need.

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Software upload

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